The 7 Best Vitamins and Minerals for Your Immune System
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October 13, 2025/Diet, Food & Fitness/Nutrition
7 Vitamins and Minerals That Help Boost Your Immunity
Eat your fill of vitamins C, B6 and E, plus zinc and selenium
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Variety of vitamin- and mineral-rich foods, including salmon, eggs, milk, nuts, spinach and oranges
The old saying, “An apple a day keeps the doctor away,” may have some truth behind it, after all. Eating nourishing foods rich in certain vitamins and minerals can help your immune system fight off illness.
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“A <a href="https://my.clevelandclinic.org/health/articles/21196-immune-system” rel=”nofollow noopener” target=”_blank”>strong immune system bolsters your body against the common cold and the flu,” says registered dietitian Julia Zumpano, RD, LD. “It can also help you recover from injury and keep your energy level high.”
Zumpano shares the best minerals and vitamins for your immune system.
1. Vitamin A
Vitamin A supports your white blood cells and the mucus membranes (protective linings that remove foreign particles) in your urinary tract, intestines and lungs. Research shows that this helps keep your immune system at its best by protecting it from potential infections.
- Milk and yogurt
- Eggs
- Fatty fish, like salmon and mackerel
- Vegetables, like sweet potatoes, carrots, spinach and broccoli
2. Vitamin B6
Vitamin B6 is vital to your immune system. One of its major roles is in producing white blood cells and T cells — the cells that help fight off invaders, like viruses and bacteria.
- Chickpeas
- Beef
- Salmon
- Tuna
- Tofu
3. Vitamin C
Vitamin C is one of the best vitamins to boost your immune system. In fact, researchers say vitamin C deficiency can make you more prone to getting sick. Vitamin C acts as an antioxidant, meaning it can protect your body from toxins that cause inflammation.
Getting your intake of vitamin C on the regular is essential for good health because your body doesn’t produce it on its own. It also doesn’t store it for later.
Foods high in vitamin C include:
- Bell peppers
- Citrus fruits
- Kale
“The good news is that vitamin C is in so many foods that most people don’t need to take a vitamin C supplement unless a doctor advises it,” notes Zumpano.
4. Vitamin D
Vitamin D doesn’t just help your body defend itself against infection. It also promotes healing. Studies show that vitamin D may delay a virus’s ability to replicate, reduce inflammation and increase your T cell levels.
You can get vitamin D from foods like:
- Fatty fish, like trout and salmon
- Canned fish, like sardines and tuna
- Egg yolks
- Mushrooms
- Fortified orange juice
“Your body naturally produces vitamin D when you’re in the sun. Daily exposure to direct sunlight is the best way to meet your needs of this essential vitamin,” says Zumpano. “There aren’t many whole foods that are goods from food alone.”
5. Vitamin E
Vitamin E is a powerful antioxidant that helps your body fight off infection. Research shows that vitamin E is one of the most effective nutrients for your immune function. That’s because it helps keep your T-cells working at peak performance.
Zumpano strongly encourages avoiding vitamin E supplements.
“Not only is there little clinical research showing that vitamin E supplements benefit your health, but they may also be harmful in some situations,” she warns.
Instead, load up your plate with vitamin E-filled foods, like:
- Sunflower seeds
- Almonds
- Broccoli
- Avocado
6. Zinc
Zinc is anti-inflammatory and an antioxidant. Researchers call it the “gatekeeper” of your immune system because it’s responsible for making all your immune cells function properly.
Foods to boost your zinc intake include:
- Oysters
- Lean cuts of beef
- Pumpkin seeds
- Turkey breast
7. Selenium
Dietary selenium is a one-two punch for keeping you healthy. It not only activates your immune system when there’s a threat, but it also tells your immune system when to pump the brakes.
That means it can keep your immune system from going overboard, protecting you from chronic inflammation and autoimmune diseases, like rheumatoid arthritis, Crohn’s disease and psoriasis.
- Brazil nuts
- Tuna
- Halibut
- Cottage cheese
Should I take vitamin supplements to boost my immune system?
While vitamin supplements can help fill the gaps in your diet, the best way to load up on essential nutrients is to get them straight from the source.
“Your body absorbs and uses vitamins and minerals better when they come from the foods you eat than from a supplement,” Zumpano stresses.
Plus, supplements aren’t monitored by the U.S. Food and Drug Administration (FDA). Some of them can have side effects, especially if you take them before surgery or with other medicines. Supplements can also cause problems if you have certain health conditions. And the effects of many supplements haven’t been tested in children, pregnant women and other groups.
For these reasons, experts say it’s best to get your vitamins and minerals through food rather than use supplements to improve your immune system.
If you think you need a supplement, Zumpano suggests talking with a healthcare provider first.
“They can help you understand whether a supplement is right for you,” concludes Zumpano. “They can advise you on how to get your fill of the nutrients your body needs.”
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